Insight into the Stunting vis a vis Salmonella and Shigella Species among Children of Pakistan

Autor: Noreen Z, Bokhari H, Batool M, Krishin J
Rok vydání: 2021
Předmět:
Zdroj: Journal of Bacteriology and Mycology. 8
ISSN: 2471-0172
DOI: 10.26420/jbacteriolmycol.2021.1172
Popis: Pakistan is one of the leading countries where the high childhood mortality (under the age of 5 years) as well as is a country where >33% of children are underweight and 38% show stunted growth. The current study investigated the presence or absence of Salmonella and Shigella sp. in stunted children under five years of age from the lower socioeconomic background of Pakistan. Besides, the antibiotics susceptibility patterns were studied along with the sociodemographic and clinical information demographic factors using a questionnaire. The stool samples from stunted children have processed following standard bacteriological protocols and presumptive colonies of Salmonella and Shigella species were identified and sub-cultured on selective media and confirmed by using the standard biochemical test as well as molecular tests. Antibiotics susceptibility of the isolates to 10 antibiotics was tested using disk diffusion assay. The results suggested that 10.5% and 5.7% of the stool samples were positive for Salmonella and Shigella sp. respectively. Moreover, the antibiotics susceptibility test results of the isolates showed that Salmonella sp., were showing higher resistance to amoxicillin whereas Shigella sp. were more resistant to gentamycin. All Salmonella and Shigella isolates were resistant to Rifampicin and 80% of isolates of both were susceptible to ciprofloxacin and cefotaxime. The study suggested that environmental enteric dysfunction (EED), is widespread among malnourished children and may result in stunted growth. The contributory factors such as unsafe farming practices or close association to poultry or livestock animals and prevailing sanitation & hygiene conditions are the potential source of entero-pathogens.
Databáze: OpenAIRE