Clinical safety and hemodynamic, cardiac autonomic and inflammatory responses to a single session of inspiratory muscle training in obstructive sleep apnea
| Autor: | Virgínia Maria Barros de Lorena, Anna Myrna Jaguaribe de Lima, Thayse Neves Santos Silva, Maria do Socorro Brasileiro-Santos, Michelle Christiane da Silva Rabello, Sílvia Thamilis Barbosa Pessoa Ferreira, Juliana Baptista Teixeira, Breno Quintella Farah |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
Neurology business.industry Hemodynamics Sleep apnea medicine.disease law.invention Obstructive sleep apnea 03 medical and health sciences 0302 clinical medicine Blood pressure 030228 respiratory system Otorhinolaryngology Randomized controlled trial law Internal medicine Heart rate cardiovascular system medicine Cardiology Heart rate variability cardiovascular diseases Neurology (clinical) business 030217 neurology & neurosurgery |
| Zdroj: | Sleep and Breathing. 26:99-108 |
| ISSN: | 1522-1709 1520-9512 |
| Popis: | To determine clinical safety and cardiovascular, cardiac autonomic and inflammatory responses to a single session of inspiratory muscle training (IMT) in obstructive sleep apnea (OSA) subjects. In a randomized controlled trial individuals of both sexes, aged between 30 and 70 years old with diagnosis of moderate to severe OSA were enrolled. Volunteers with OSA (n = 40) performed an IMT session with three sets of 30 repetitions with a 1-min interval between them. The IMT group (n = 20) used a load of 70% of the maximum inspiratory pressure (MIP), and the placebo group (n = 20) performed the IMT without load. Measurements of systolic blood pressure (SBP), diastolic blood pressure (DBP), heart rate (HR), heart rate variability (HRV), and inflammatory markers were performed pre, post-immediate and 1 h after the IMT session. No differences were shown in SBP, DBP, HRV, or inflammatory markers at any of the intervals analyzed. However, HR in the IMT group was lower 1 h after the IMT session compared to the pre-session values (p = 0002). HR was higher in the placebo group when comparing pre × post-immediate (p < 0.001). HR decreased after the first hour in relation to the pre (p < 0.001) and post-immediate (p < 0.001) values. IMT sessions promote discreet hemodynamic, cardiac autonomic and inflammatory responses. Therefore, IMT is considered clinically safe and can be performed at home, guided but unsupervised, with lower cost and greater adherence to exercise program for subjects with OSA. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full text from SpringerLink