An enantiocontrolled synthesis of pyrrolizidines, (−)-platynecine and (−)-hadinecine

Autor:	Sung Ho Kang, Yong Sang Yoo, Geun Tae Kim
Rok vydání:	1997
Předmět:	Allylic rearrangement Chemistry Stereochemistry Platynecine Organic Chemistry Enantioselective synthesis Biochemistry chemistry.chemical_compound Intramolecular force Drug Discovery Pyrrolizidine Retronecine Amine gas treating Heliotridine
Zdroj:	Tetrahedron Letters. 38:603-606
ISSN:	0040-4039
DOI:	10.1016/s0040-4039(96)02371-4
Popis:	Trisubstituted allylic alcohols 13 and 14 have been converted into a single isomeric trans-oxazoline 16 via an intramolecular iodoamidation of the corresponding trichloro-acetimidates, which have been elaborated into (−)-platynecine 1 and (−)-hadinecine 2 via a common intermediate pyrrolizidine 3.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::267f82938d7177e516f38c585a23af11 https://doi.org/10.1016/s0040-4039(96)02371-4 Zobrazit plný text záznamu Full Text from ScienceDirect