Tackling the increasing complexity of therapeutic monoclonal antibodies with mass spectrometry

Autor:	Sara Rosati, Natalie J. Thompson, Albert J.R. Heck
Rok vydání:	2013
Předmět:	Bispecific antibody Glycosylation Chromatography biology medicine.drug_class Biosimilar Computational biology Monoclonal antibody Mass spectrometry Analytical Chemistry chemistry.chemical_compound Biopharmaceutical chemistry biology.protein medicine Antibody Spectroscopy
Zdroj:	TrAC Trends in Analytical Chemistry. 48:72-80
ISSN:	0165-9936
DOI:	10.1016/j.trac.2013.02.013
Popis:	Mass spectrometry (MS) is emerging as an efficient method for the structural analysis of various new antibody-based therapeutic products. Here, we review the current trends and describe recent applications that highlight the use of MS to tackle the increasing complexity of monoclonal antibodies.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::263ea614f11f20d55ed398a4e01efc45 https://doi.org/10.1016/j.trac.2013.02.013 Zobrazit plný text záznamu Full Text from ScienceDirect