Spatial Organization of the Transport of Interstitial Fluid and Lymph in Rat Liver (Scanning Electron Microscopy of Injection Replicas)
| Autor: | Keti Tsomaia, D Kordzaia, S. A. Gusev, L. G. Patarshvili, Irakli Bebiashvili |
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| Rok vydání: | 2021 |
| Předmět: |
0301 basic medicine
Pathology medicine.medical_specialty Common bile duct Scanning electron microscope Chemistry General Medicine General Biochemistry Genetics and Molecular Biology Microcirculation 03 medical and health sciences 030104 developmental biology 0302 clinical medicine Lymphatic system medicine.anatomical_structure Interstitial space Interstitial fluid medicine Lymph Perivascular space 030217 neurology & neurosurgery |
| Zdroj: | Bulletin of Experimental Biology and Medicine. 170:395-399 |
| ISSN: | 1573-8221 0007-4888 |
| DOI: | 10.1007/s10517-021-05074-x |
| Popis: | Using the method of scanning electron microscopy of injection replicas, we studied the movement of a new injection mass between the blood microcirculation system, interstitial space, lymphatic system, and bile transport system in rat liver under normal conditions and 3 days after the occlusion of the common bile duct. The casts of the perisinusoidal spaces of Disse’s after injection of the injection mass through the portal vein and common bile duct were obtained. Their direct transition not only in “leakages” structurally related to lymphatic capillaries in interlobular spaces, but also in perivascular spaces around the portal and hepatic veins. The flow of the injection mass through the perivascular spaces leads to the formation of peculiar “sheaths” around hepatic veins and components of the portal complex. The proposed approach allows effective visualization of the structural basis of interaction of various compartments of the fluid microcirculation in the liver under normal and pathological conditions. |
| Databáze: | OpenAIRE |
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