First description of posterior reversible encephalopathy syndrome as a complication of glycerolnitrate patch following open cardiac surgery

Autor: G. Wendt, G. Dooms, B. Huch, A.L. Kühn, D. W. Droste
Rok vydání: 2010
Předmět:
Zdroj: Acta Neurologica Scandinavica. 124:218-220
ISSN: 0001-6314
DOI: 10.1111/j.1600-0404.2010.01445.x
Popis: Kuhn AL, Huch B, Wendt G, Dooms G, Droste DW. First description of posterior reversible encephalopathy syndrome as a complication of glycerolnitrate patch following open cardiac surgery. Acta Neurol Scand: 2011: 124: 218–220. © 2010 John Wiley & Sons A/S. Background– Posterior reversible encephalopathy syndrome (PRES) affects predominantly the parietal and occipital lobes. Frequent clinical features are epileptic seizure, altered mental status and visual disturbances. Clinical Presentation – We present the first case of a patient with pericarditis and mitral valve insufficiency, who developed PRES after application of a glycerolnitrate patch day three post-operatively and whose neurological deficits improved within 2 days after withdrawal of patch therapy. Conclusion – The precise pathomechanism of PRES is unknown. The lower sympathetic innervation of the posterior circulation may be one explanation for its particular vulnerability to vasodilatation caused by glycerolnitrate.
Databáze: OpenAIRE