Late Breaking Abstract - Validation of a clinical score predictive of SARS-CoV-2 infection in pneumonia inpatients
| Autor: | Ana Alfaiate, Vera Durão, Susana Sousa, F. Durão, David Noivo, Margarida Castanho, Paula Duarte, Vera Clérigo |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
Framingham Risk Score Scoring system Coronavirus disease 2019 (COVID-19) business.industry Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) medicine.disease Community hospital 03 medical and health sciences Pneumonia 0302 clinical medicine 030228 respiratory system Intensive care Internal medicine Cohort medicine 030212 general & internal medicine business |
| Zdroj: | Respiratory infections. |
| DOI: | 10.1183/13993003.congress-2020.3595 |
| Popis: | Background: Early identification of patients (pts) with the novel coronavirus disease 2019 (COVID-19) and pneumonia is currently challenging. Few data is available on validated scores predictors of SARS-CoV-2 infection. The Portuguese Society of Intensive Care proposed a risk score, allowing an optimization of hospital resources and adjusted patients’ intervention. Aims: To validate a clinical score applied to hospitalized pneumonia pts, predicting higher probability of COVID-19, based on a single-center department cohort. Methods: The authors performed a retrospective analysis of 207 pneumonia pts admitted in a specialized department for suspected/confirmed SARS-CoV-2 infection of a community hospital from 20/03 to 20/05/2020. The score variables and punctuation were registered, in order to determine the independent predictive variables and the score cut-off for COVID-19. Score accuracy was measured by the AUC. Results: The validation cohort included 145 pts (62 were excluded due to lack of information on one or more score variables). Mean age was 69.90±17.77 years and 81 (55.86%) were males. Thoracic CT typical abnormalities (OR, 12.16; 95% CI, 3.32-44.50) and SARS-CoV-2 positive pt contact (OR, 6.56; 95% CI, 1.33-32.30) were independent predictive factors. A score ≥ 10 can increase suspicion for SARS-CoV-2 pneumonia. AUC was 0.82 (95% CI, 0.73-0.91) demonstrating the accuracy of the scoring system for COVID-19 probability stratification in pneumonia pts. Conclusion: The application of this risk score to ward pts admitted for pneumonia may be of value in predicting the risk of COVID-19. Further studies from other centres are needed to validate this score more widely. |
| Databáze: | OpenAIRE |
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