Occult diffuse involvement of supratentorial white matter detected by magnetic resonance imaging in HTLV-I carriers
| Autor: | Shinsuke Yamauchi, Tatsuru Niimura, Kiyoshige Niina, Yoichi Hokezu, Ikuro Maruyama, Mitsuhiro Osame, Shinji Ijichi |
|---|---|
| Rok vydání: | 1994 |
| Předmět: |
Pathology
medicine.medical_specialty biology medicine.diagnostic_test business.industry Cerebral white matter Central nervous system Magnetic resonance imaging Human T-lymphotropic virus biology.organism_classification Occult Asymptomatic Hyperintensity White matter medicine.anatomical_structure medicine medicine.symptom business |
| Zdroj: | Japanese Journal of Tropical Medicine and Hygiene. 22:117-120 |
| ISSN: | 2186-1811 0304-2146 |
| DOI: | 10.2149/tmh1973.22.117 |
| Popis: | We describe three human T lymphotropic virus type I (HTLV-I) carriers, who are characterized by a dissociation between the clinical features including scarce cognitive impairments and peculiar hyperintensities in the deep and subcortical white matter detected by T2-weighted magnetic resonance imaging (MRI) scans. Unlike spotty MRI findings which are encountered in clinically asymptomatic elderly individuals and are previously described in some HTLV-I carriers, the MRI changes in our patients were diffuse and extensive. Known central nervous system disorders accompanying a cerebral white matter involvement were failed to be diagnosed. These findings support a possibility that extensive lesions in the supratentorial white matter are associated with HTLV-I infection with minimal symptoms, and suggest that MRI scans may detect occult diffuse inflammatory changes associated with the virus infection in these patients. |
| Databáze: | OpenAIRE |
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