Double-blind comparison of alclofenac and aspirin in the treatment of rheumatoid arthritis
| Autor: | Bedi Ss |
|---|---|
| Rok vydání: | 1975 |
| Předmět: | |
| Zdroj: | Current Medical Research and Opinion. 3:309-320 |
| ISSN: | 1473-4877 0300-7995 |
| Popis: | SummaryA double-blind trial was carried out in 76 patients with active rheumatoid arthritis to compare the analgesic and anti-inflammatory activity of 3 g. alclofenac with 4.8 g. aspirin daily over a 6-week period. All patients selected showed reversible inflammatory swelling of the finger joints. Of the 60 patients successfully completing the trial, 30 were treated as out-patients and 30 patients received in-patient treatment for approximately the first 2 weeks. Both groups were analysed separately. Treatment was randomised and patients received the drugs in identical tablet form except for the last 16patients who were transferred to capsules.Results showed that though the activity potential, morning stiffness, grip strength, joint pain and tenderness improved significantly at the end of the 6-week period, there was no statistical difference between the two drugs. However, functional capacity indicated slight superiority of alclofenac over aspirin at a low level of significance. P. I.P. joint swelling sh... |
| Databáze: | OpenAIRE |
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