A Search for Helicobacter pyloriin Localized Vulvodynia
| Autor: | Josef Levy, Adam Geva, Edmond Sabo, Hana Geva, Jacob Bornstein, Ella Ophir, Monique Blumenthal |
|---|---|
| Rok vydání: | 2008 |
| Předmět: |
Gynecology
medicine.medical_specialty biology medicine.diagnostic_test business.industry Spirillaceae Peptic Vulvar vestibulitis Obstetrics and Gynecology Helicobacter pylori biology.organism_classification medicine.disease Gastroenterology Vulva medicine.anatomical_structure Reproductive Medicine Internal medicine medicine Vulvodynia Blood test Helicobacter medicine.symptom business |
| Zdroj: | Gynecologic and Obstetric Investigation. 66:152-156 |
| ISSN: | 1423-002X 0378-7346 |
| DOI: | 10.1159/000135712 |
| Popis: | Background: We noted that several patients presenting with both localized vulvodynia (vulvar vestibulitis) and peptic symptoms reported a resolution of dyspareunia after receiving a full treatment course for Helicobacter pylori. Methods: Women with localized vulvodynia were interviewed regarding symptoms of peptic disease. Those with peptic symptoms underwent a blood test for the presence of antibodies to H. pylori and were referred to a gastroenterology consultation. In all women, vestibular biopsies were obtained and stained for H. pylori. Healthy vestibular tissues as well as archival negative and positive gastric tissues served as controls. Results: Of the blood antibody tests, 12 (80%) were positive. None of the patients had evidence of H. pylori in the vestibule. Eleven women received triple therapy for eradication of H. pylori. Eight (73%) reported complete relief of dyspareunia and of gastric symptoms. Conclusion: Our study found no immunohistochemical evidence of H. pylori infection in the vestibule but suggested a possible role for anti-H. pylori treatment in localized vulvodynia. |
| Databáze: | OpenAIRE |
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