Chemoselective Synthesis of β-Amino Ester or β-Lactam via Sonochemical Reformatsky Reaction

Autor: Yu-Ting Chang, Feng-Yi Su, Adam Shih-Yuan Lee
Rok vydání: 2013
Předmět:
Zdroj: Journal of the Chinese Chemical Society. 61:290-294
ISSN: 0009-4536
Popis: A series of β-amino esters were synthesized by the reaction of N-tosyl aldimine or N-hydroxy aldimine with bromoacetate by sonochemical Reformatsky reaction. The β-N-hydroxyamino ester was obtained and the formed sensitive hydroxylamino functionality was resistant under the reaction condition. The β-lactam also was synthesized by the reaction of N-p-methoxy aldimine as reacting substrate under this sonochemical Reformatsky reaction condition.
Databáze: OpenAIRE