A catalyst- and solvent-free multicomponent synthesis of 7-azagramine analogues via a Mannich type reaction

Autor:	Pravin S. Bhale, Babasaheb P. Bandgar, Yoginath B. Mule, Amol S. Kotmale, Sakharam B. Dongare, Hemant V. Chavan
Rok vydání:	2016
Předmět:	Solvent free 010405 organic chemistry Chemistry Proton NMR Organic chemistry General Chemistry 010402 general chemistry 01 natural sciences Mannich reaction Heteronuclear single quantum coherence spectroscopy 0104 chemical sciences Catalysis
Zdroj:	Chinese Chemical Letters. 27:99-103
ISSN:	1001-8417
DOI:	10.1016/j.cclet.2015.07.029
Popis:	A catalyst- and solvent-free protocol for the synthesis of 7-azagramine analogues is described via a three-component Mannich type reaction between 7-azaindole, aromatic aldehydes and heterocyclic amines in acceptable to excellent yields. Structures of the compounds were confirmed satisfactorily by 1 H NMR, IR, mass, TOCSY, HSQC and HMBC spectral analyses.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::21c488bfc9b5f77811c1f63e432d28ca https://doi.org/10.1016/j.cclet.2015.07.029 Zobrazit plný text záznamu Full Text from ScienceDirect