Homology Models of Coronavirus 3CLpro Protease
Autor: | Martin J. Stoermer |
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Rok vydání: | 2020 |
Předmět: | |
DOI: | 10.26434/chemrxiv.11637294.v2 |
Popis: | A regional outbreak of pneumonia in Wuhan, Hubei Province of China in late 2019 was associated with a novel coronavirus. Rapid release of genomic data for the isolated virus enabled the construction of first-generation homology models of the new CoV 3CLpro cysteine protease. Whilst the overall viral genome was most closely associated with bat coronaviruses, the main protease is most closely related (96% identity) to SARS CoV protease. |
Databáze: | OpenAIRE |
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