A Comparison of Urine Sample to Urethral Swab for Detection of Chlamydia trachomatis in Asymptomatic Young Men Using Two Enzyme Immunoassays
| Autor: | Jensen Ip |
|---|---|
| Rok vydání: | 1991 |
| Předmět: |
Microbiology (medical)
Gynecology medicine.medical_specialty biology business.industry Public Health Environmental and Occupational Health Prevalence Dermatology Urine biology.organism_classification medicine.disease medicine.disease_cause Asymptomatic Infectious Diseases Chlamydiales medicine Chlamydiaceae Urethritis medicine.symptom business Chlamydia trachomatis Asymptomatic carrier |
| Zdroj: | Sexually Transmitted Diseases. 18:165-169 |
| ISSN: | 0148-5717 |
| DOI: | 10.1097/00007435-199105000-00011 |
| Popis: | First catch early morning urine samples were compared to urethral swabs for detection of Chlamydia trachomatis in 405 male military conscripts, using 2 enzyme immunoassays, Syva Microtrak EIA (SME) and ABBOTT Chlamydiazyme (AC). The prevalence rate of C. trachomatis was 7.9% (95% confidence limits 5.5%-11.0%), and the asymptomatic carrier rate was 7.8% (95% confidence limits 5.2%-11.2%). Only 5 of 32 conscripts with positive test results for C. trachomatis complained of urethritis symptoms, and of 13 conscripts with symptoms, only 5 had positive test results for C. trachomatis. The sensitivity of SME in detecting C. trachomatis was 82.1% for both urine samples and urethral swabs. Assayed with AC, the sensitivity was 62.1% for urine samples and 41.4% for urethral swabs (P greater than 0.05). With urine as specimen type, the sensitivity of SME was 82.8% and the sensitivity of AC was 62.1% (P greater than 0.05). With urethral swab as specimen type, the sensitivity of SME was 92.3% and the sensitivity of AC was 46.1% (P less than 0.01). In all assays, the specificity was at least 98.0%. First catch early morning urine seems to be a valid specimen type for the detection of C. trachomatis in young men in comparison to ordinary urethral swab specimens. It is a noninvasive method and suitable for screening of asymptomatic young men. |
| Databáze: | OpenAIRE |
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