2-Phenyl Oxazolone

Autor: Jetze J. Tepe, Nicole M. Hewlett
Rok vydání: 2014
Předmět:
Zdroj: e-EROS Encyclopedia of Reagents for Organic Synthesis
Popis: [1199-01-5] C9H7NO2 (MW 161.16) InChI = 1S/C9H7NO2/c11-8-6-10-9(12-8)7-4-2-1-3-5-7/h1-5H,6H2 InChIKey = QKCKCXFWENOGER-UHFFFAOYSA-N (reagent used as a masked glycine equivalent and for the formation of heterocyclic structures) Alternate Name: 2-phenyl-5(4H)-oxazolone. Physical Data: mp 89–92 °C.1 Solubility: soluble in most common organic solvents. Will react with nucleophilic solvents such as methanol. Form Supplied in: light buff to yellow crystalline solid.1 Preparative Methods: typically prepared from the reaction of hippuric acid with a dehydrating agent such as 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide (EDCI)2 or acetic anhydride.1, 3 The use of other carbodiimides has also been reported.4 Handling, Storage, and Precautions: air sensitive.
Databáze: OpenAIRE