Obez bireylerde serum netrin-1 düzeyi ve obezite ile ilgili belirteçler arasındaki ilişki

Autor: Çiğdem AYDIN ACAR, Niyazi AYDIN, Suray PEHLİVANOĞLU, Mehmet KÖK
Rok vydání: 2022
Předmět:
Zdroj: Mehmet Akif Ersoy Üniversitesi Sağlık Bilimleri Enstitüsü Dergisi.
ISSN: 2148-2837
Popis: Netrins are important signaling proteins that guide both neural and vascular development. Netrin-1 regulates many physiological processes such as cell proliferation, adhesion and migration. The aim of this study was to determine the association between serum netrin-1 level and biochemical parameters in obese subjects. Serum samples were collected from obese (n=15) and control (n=30) subjects. The serum netrin-1 levels were evaluated by ELISA. Variable data were compared by Mann Whitney U test and correlation was estimated by Spearman correlation analyses. The level of circulating netrin-1 protein was determined to be significantly lower in obese group compared to controls. The median value was 844.0 pg/mL in the control group and 338 pg/mL in the obese group (p
Databáze: OpenAIRE