A review on development of bio-active thiosemicarbazide derivatives: Recent advances

Autor:	Hitesh D. Patel, Zeel A. Bhavsar, Prachi T. Acharya, Divya J. Jethava, Dhaval B. Patel
Rok vydání:	2021
Předmět:	010405 organic chemistry Chemistry Organic Chemistry 010402 general chemistry Highly selective 01 natural sciences Combinatorial chemistry 0104 chemical sciences Analytical Chemistry Molecular hybridization Inorganic Chemistry Biological profile Literature survey Spectroscopy
Zdroj:	Journal of Molecular Structure. 1226:129268
ISSN:	0022-2860 2001-2020
DOI:	10.1016/j.molstruc.2020.129268
Popis:	There has been substantial attention in the expansion of new thiosemicarbazide derivatives with diverse biological activities in recent years. Therefore, many scientists have prepared this class of derivatives as target structures and estimated their biological activities. Recent research mainly described an important collection of very effective and highly selective thiosemicarbazide analogues having various biological activities. This report is principally addressed to the account of the recent advances in the synthesis of heterocyclic compounds hybrid thiosemicarbazides and their biological profile along with structure-activity relationship (SAR) study, which can assist the expansion of different thiosemicarbazide derivatives having a wide range of medicinal applications. This review pronounces the literature survey concerning the various heterocyclic scaffolds hybrid thiosemicarbazide derivatives in the last twenty years (2001-2020).
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::1f3bbdfd56476e39510fc0b44a36f5d5 https://doi.org/10.1016/j.molstruc.2020.129268 Zobrazit plný text záznamu Full Text from ScienceDirect