Solvent-Dependent Conformations of Cyclic Tetrapeptide. II

Autor:	Tomomi Saeki, Sadatoshi Akabori, Makoto Tamaki, Ichiro Muramatsu, Mikihoro Yabu, Ayako Kaneko
Rok vydání:	1999
Předmět:	Solvent Tetrapeptide Chemistry Polarity (physics) Stereochemistry Negative peak Infrared spectroscopy Single bond General Chemistry Nmr data
Zdroj:	Bulletin of the Chemical Society of Japan. 72:733-739
ISSN:	1348-0634 0009-2673
Popis:	The solvent-dependent conformations of cyclo(–δ-Ava–L-Pro–)2 were characterized by means of the 1H and 13H NMR, CD, and IR spectra. CD results in CH2Cl2, CH3CN, CH3OH, and H2O indicated that the change in polarity of the solvent induces a reversible change in the conformation of cyclo(–δ-Ava–L-Pro–)2, revealed by the decrease of the negative peak near to 230 nm and then by the gradual appearance of a negative trough near to 210 nm. The NMR data in CD3Cl, CD2Cl2, CD3CN, and CD3OH confirmed that cyclo(–δ-Ava–L-Pro–)2 has a C2 symmetric conformation consisting of all-trans peptide-bond backbones in all solvents, and that the change in polarity of the solvent induces a difference in the rotational states of the Pro αC–C=O single bond.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::1cf86b403e059c4ab16f82000654d46f https://doi.org/10.1246/bcsj.72.733 Zobrazit plný text záznamu