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Background Early identification of post‑transplantation diabetes mellitus (PTDM) can be helpful to attenuate the rapid development of diabetic complications. This article aims to explore the beneficial values of metabolic-related markers, including TyG, TyG-BMI, TG/HDL-C and non-HDL-C/HDL-C, for predicting PTDM.Material and methods The data of 191 renal transplant recipients in our center were collected retrospectively. The association between the metabolic-related markers and the risk of PTDM was examined by the area under the curve and logistic regression analyses. Results During 6 months follow-up, 12.04% of RT recipients developed PTDM, and significantly higher values of TyG-BMI, TyG and non-HDL-C/HDL-C was found in patients with PTDM than in nondiabetic patients, especially among the recipients taking FK506. The incidence of PTDM increased along with the values of TyG or TyG-BMI. After adjusting for multiple potential factors, recipients with the highest trisector of TyG or TyG-BMI still had a higher risk of PTDM morbidity. Conclusions TyG, TyG-BMI, TG/HDL-C and non-HDL-C/HDL-C can predict PTDM in renal transplant recipients, and TyG-BMI was the best alternative marker among the four markers. TyG and TyG-BMI can be used as cost-effective and complementary monitors to identify individuals at high risk of PTDM. |
