Comparison of the Effects of a Low-fat, High-carbohydrate Diet at Two Levels of Polyunsaturates on Plasma Lipids of Patients with Familial Endogenous Hypertriglyceridemia

Autor: L. Cominacini, Loredana Brunetti, Ludovico A. Scuro, Ulisse Garbin, Anna Davoli, Ottavio Bosello
Rok vydání: 1990
Předmět:
Zdroj: Journal of Nutritional Medicine. 1:95-105
ISSN: 0955-6664
DOI: 10.3109/13590849009003143
Popis: In this study we compared the effects of a low-fat, high-carbohydrate (LFHC) diet at two levels of polyunsaturated fatty acids on plasma lipids of 20 patients affected by familial endogenous hypertriglyceridemia. During the intervention period the proportion of dietary energy derived from fat was reduced from about 45% to 20% in all the subjects. Ten patients (group I) consumed a LFHC diet with a polyunsaturated to saturated fat (P/S) ratio of 0.4, while the other 10 patients (group II) had a diet with a P/S ratio of 1–7. During the intervention period we observed a significant decrease of total plasma triglycerides and cholesterol in both groups. In spite of the different P/S ratio, the decrease of total triglycerides and cholesterol was superimposable in the two groups. The fall in plasma triglycerides and cholesterol was due only to the decrease in very low density lipoproteins (VLDL). On the contrary, low density lipoproteins (LDL) cholesterol was unchanged in both groups. Finally, during the interven...
Databáze: OpenAIRE
Nepřihlášeným uživatelům se plný text nezobrazuje