| Popis: |
Background: Epilepsy disease, which negatively affects 65 million people around the world, can be seen in all age groups regardless of gender. Disease is known throughout the history of human disease, although the mechanism is still unknown. In this study, it is aimed to investigate of apelin and oxidative stress levels in children with epilepsy. Materials and methods: Children with epilepsy (aged 0-16) who had been diagnosed with epilepsy and did not start treatment were included in the study. This study included control group healthy normal children (n=28) and children with epilepsy group (n=28), totally 56 children were included. Blood samples were removed for apelin, advanced protein oxidation product (AOPP) and DNA damage marker 8-Hydroxy 2-Deoxyguanosine (8-OHdG) levels analyses by ELISA method. Results: Apelin level in generalized type epilepsy was lower than the control group and the complicated febrile group (p |
