Theoretical description of modern1H in Vivo magnetic resonance spectroscopic pulse sequences

Autor: Rolf F. Schulte, Michael S. Treacy, Karl Landheer, Christoph Juchem, Kelley M. Swanberg
Rok vydání: 2019
Předmět:
Zdroj: Journal of Magnetic Resonance Imaging. 51:1008-1029
ISSN: 1522-2586
1053-1807
Popis: This article reviews the most commonly used modern sequences designed to confront the two major challenges of in vivo magnetic resonance spectroscopy (MRS): spatial localization and metabolic specificity. The purpose of this review article is to provide a deeper and clearer understanding of the underlying mechanisms by which all modern MRS sequences operate. A descriptive explanation, consistent pulse sequence diagram, and theoretical concepts of the measured signal are given for five spatial localization sequences and three modules designed to increase metabolic specificity. Cross-sequence comparisons, including potential modifications for estimating quantitative measures like spin-lattice relaxation time T1 , spin-spin relaxation time T2 , and diffusion coefficients are briefly discussed. Level of Evidence: 5 Technical Efficacy Stage: 1 J. Magn. Reson. Imaging 2020;51:1008-1029.
Databáze: OpenAIRE