Idiopathic Thrombocytopenic Purpura in Post COVID-19 Condition: Case Study

Autor: Kommuri Vyduryam, R. Piety Christiana, K. Sravya, A. Javed Akhtar, P. Joy Nissi, V. Pravallika, Ch. K. V. L. S. N. Anjana Male, N. V. Yaseswi
Rok vydání: 2021
Předmět:
Zdroj: Journal of Pharmaceutical Research International. :25-31
ISSN: 2456-9119
DOI: 10.9734/jpri/2021/v33i42a32380
Popis: A 50 years old woman was referred to hospital with complaints of bluish black discoloration of skin or multiple ecchymosis since 6 days and skin rashes, pink changes or petechiae changes since 1 week, dark color stools since 3 days. She had a history of COVID-19 positive on past ‘‘3 months’’ back and she received the corticosteroids, antiviral drugs, broad spectrum antibiotics, anticoagulants, and vitamin B and C supplements. Now patient is admitted and investigated for further management. Her bone marrow examination reveals marrow cytological features are compatible with immune thrombocytopenic Purpura and peripheral examination reveals red cells are microcytic hypochromic with elongation forms, platelets are markedly reduced and elevation of CRP, reduction of the Hb, PCV, MCH, MCV, MCHC, APTT, Serum vitamin B12, Lymphocytes and her HRCT-Chest shows CORADS 5, Rapid antigen test shows positive. A review on introduction of the disease, etiology, pathogenesis, pathophysiology, mechanism of thrombocytopenia in COVID-19 patients and grading is explained in literature review.
Databáze: OpenAIRE