A New Route to 3-Phenoxybenzyl cis (±) 2,2-Dimethyl-3-(2-Phenyl-2-Chlorovinyl) Cyclopropanecarboxylate

Autor:	A. R. A. S. Deshmukh, Z. Muljiani, R. B. Mitra
Rok vydání:	1982
Předmět:	Chemistry Organic Chemistry Organic chemistry Cyclopropanecarboxylic acid Mammalian toxicity
Zdroj:	Synthetic Communications. 12:1063-1070
ISSN:	1532-2432 0039-7911
DOI:	10.1080/00397918208061948
Popis:	Synthetic pyrethroids belong to an almost ideal group of modern insecticides due to their high insecticidal activity, low mammalian toxicity and rapid biodegradability.1 While several pyrethroids with potent insecticidal action have been synthesized, search for analogues with high photostability and other pesticidal activity continues. In this connection some esters of 2,2-dimethyl-3-(2-phenyl-2-chlorovinyl) cyclopropane-carboxylic acid have recently been reported to have good acaricidal activity2–4 as well. Structure-activity relationship reveals that for the synthetic pyrethroids, esters of cis-substituted cyclopropanecarboxylic acid show far superior activity compared to the corresponding trans-isomer. Most of the methods described in the literature5 lead to a mixture of cis and trans-substituted cyclopropanecarboxylic acids.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::1b8aeb2e31e9db43297f0a2c8d30fbd8 https://doi.org/10.1080/00397918208061948 Zobrazit plný text záznamu