Transmission Electron Microscopy of Fine Needle Aspiration Biopsies of Metastases

Autor:	Guillermo Quinonez, Delia Jara Facundo, Esther Ravinsky
Rok vydání:	2003
Předmět:	Leiomyosarcoma medicine.medical_specialty Histology medicine.diagnostic_test business.industry General Medicine medicine.disease Pathology and Forensic Medicine Fine-needle aspiration Cytopathology Cytology Biopsy medicine Carcinoma Adenocarcinoma Sarcoma Radiology business
Zdroj:	Acta Cytologica. 47:457-462
ISSN:	1938-2650 0001-5547
DOI:	10.1159/000326550
Popis:	OBJECTIVE: To determine the accuracy of fine needle aspiration biopsy in establishing the primary on cytology and on cytologic and electron microscopy examinations using tissue biopsy as the gold standard. STUDY DESIGN: A retrospective study of 96 nonrandomly selected cases of metastases with an unknown primary was carried out. Tissue biopsy was performed subsequently for confirmation. Proper clinical correlation was part of the analysis. RESULTS: The accuracy of cytology in identifying the tumor category (e.g., carcinoma, sarcoma) and tumor type (e.g., adenocarcinoma, leiomyosarcoma) was 76% and 78%, respectively, while that of electron microscopy was 95% and 91%, respectively. The primary site was correctly identified by cytology in 59% and by electron microscopy in 88% of cases, provided that clinical parameters were also considered. CONCLUSION: Electron microscopy is an ancillary technique useful in increasing the accuracy of tumor classification of metastatic neoplasms identified by fine needle aspiration biopsy.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::1b74907619b3190e10c8e9d0c2c8daac https://doi.org/10.1159/000326550 Zobrazit plný text záznamu