Parentage testing following an infanticide case using fetal DNA from archival fixed tissues

Autor:	Dan Dermengiu, Ligia Elena Barbarii
Rok vydání:	2003
Předmět:	Genetics chemistry.chemical_compound Fetal dna DNA profiling chemistry Pcr assay General Medicine Biology Amelogenin Paraffin embedded DNA Str profiling
Zdroj:	International Congress Series. 1239:613-616
ISSN:	0531-5131
DOI:	10.1016/s0531-5131(02)00325-4
Popis:	Genetic investigation of an old infanticide case was conducted using DNA from archival fixed tissues in an attempt to provide independent evidence of the parents identity. The initial PCR assays using DNA extracted from paraffin embedded tissues failed because of possible inhibitors, requiring additional purifying steps. STR profiling was conducted on nine loci plus Amelogenin using PAGE gels. Comparison of the fetal DNA profile with the DNA profiles of the putative mother and her husband revealed the compatibility of the fetal DNA profile with the maternal profile and excluded the man from the paternity.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::19431c14632a49675f6a4fe99afc1f5a https://doi.org/10.1016/s0531-5131(02)00325-4 Zobrazit plný text záznamu Full Text from ScienceDirect