Induction of Micronuclei, Base-pair Substitution Mutation and Excision-repair Deficient by Polluted Water from Asa River in Nigeria
| Autor: | Oladipupo O Rasheedat, Adebayo O Mutolib, Ojo T Ifeoluwa, Adetunji A Kehinde, Tijani O Sherifat, Adebiyi A Koyumat, Adegbenro A Monsuru, Abdulkareem I Saratu, Eboh O Solomon, Oladipo S Olayinka, Anifowoshe T Abass, Abdussalam A Rasheedat, Yekeen O Habeeb |
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| Rok vydání: | 2019 |
| Předmět: |
0303 health sciences
History Chemistry Point mutation 010501 environmental sciences 01 natural sciences Molecular biology Computer Science Applications Education 03 medical and health sciences Micronucleus test Mutation (genetic algorithm) 030304 developmental biology 0105 earth and related environmental sciences Nucleotide excision repair |
| Zdroj: | Annals of Science and Technology. 4:68-77 |
| ISSN: | 2544-6320 |
| Popis: | Asa river is a major river designated to supply millions of people of Ilorin, Kwara State, Nigeria potable water for drinking but its managements is of grave concern due to anthropogenic activities. Thus, evaluation of genotoxicity of this river was carried out by subjecting the water samples and fish therein to three bioassays (Micronucleus (MN) assay, Ames test and SOS-chromo test). Physicochemical parameters and heavy metals were analysed at three different stations (Aliara (SI), Unity (SII) and Tuyil (SIII)) of the river. In SII, most of the heavy metals analysed were above the acceptable limits compare to SI and SIII. The peripheral erythrocyte of the fishes (Oreochromis niloticus, Synodontis batensoda, Synodontis eupterus, Clarias gariepinus and Clarias angullaris) at SI and SII stations showed a significant (pSalmonella typhimurium TA100) and SOS chromotests (Escherichia coli PQ37) at 25%, 50% and 100% concentrations showed statistically significant (p |
| Databáze: | OpenAIRE |
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