Synthesis of the betulin dipropionate from the upper birch bark

Autor:	Boris N. Kuznetsov, V. A. Sokolenko, Galina P. Skvortsova, Svetlana A. Kuznetsova, Yu. N. Malyar
Rok vydání:	2012
Předmět:	Betulin Organic Chemistry Carbon-13 NMR Biochemistry Acylation chemistry.chemical_compound chemistry visual_art Proton NMR visual_art.visual_art_medium Organic chemistry Bark Gas chromatography Fourier transform infrared spectroscopy Superheated water Nuclear chemistry
Zdroj:	Russian Journal of Bioorganic Chemistry. 38:743-748
ISSN:	1608-330X 1068-1620
DOI:	10.1134/s1068162012070126
Popis:	A one-step synthesis of the betulin dipropionate directly from the birch bark without a separate stage of the betulin preparation is described in this paper. Extracts with different content of the betulin dipropionate were shown to form depending on the conditions of acylation of the upper birch bark with propionic acid. The product with the maximum content of the betulin dipropionate was prepared from the starting fraction of 2–5 mm of the upper birch bark and the fraction of 10–20 mm that was preliminarily activated with superheated water vapor. The upper bark extract was analyzed by gas chromatography. The structure of betulin dipropionate was confirmed by element analysis, 1H NMR, 13C NMR, and FTIR spectroscopy.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::191d6a054089bd131f1f473221346fee https://doi.org/10.1134/s1068162012070126 Zobrazit plný text záznamu Full text from SpringerLink