| Autor: |
Pool Er, Patrik Vuilleumier, Yoann Stussi, David Sander, Sylvain Delplanque, David Munoz Tord, Donato Cereghetti |
| Rok vydání: |
2021 |
| Předmět: |
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| DOI: |
10.1101/2021.05.02.442349 |
| Popis: |
The ventral striatum is implicated in the affective processing of the reward, which can be divided into a motivational and a hedonic component. Here, we examined whether these two components rely on distinct neural substrates within the ventral striatum in humans. We used a high-resolution fMRI protocol targeting the ventral striatum combined with a Pavlovian-instrumental task and a hedonic reactivity task. Both tasks involved an olfactory reward, thereby allowing us to measure Pavlovian-triggered motivation and sensory pleasure for the same reward within the same participants. Our findings show that different subregions of the ventral striatum are dissociable in their contributions to the motivational and the hedonic component of the affective processing of the reward. Parsing the neural mechanisms and the interplay between Pavlovian incentive processes and hedonic processes might have important implications for understanding compulsive reward-seeking behaviors such as addiction, binge eating, or gambling. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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