STUDY OF THE INFLUENCE OF 6-(40 -IODOPHENYL)-2,3-DIHYDRO [2,1-B] THIAZOLE AT THYROID FUNCTION MALE WHITE RATS WITH EXPERIMENTAL AUTOIMMUNE THYROIDITIS
| Autor: | F. G. Yaremenko, A. V. Spiridonov, I. V. Komarova, N. G. Malova, A. N. Sova, L. A. Sirotenko, E. S. Anikeeva, V. N. Vakula |
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| Rok vydání: | 2016 |
| Předmět: |
endocrine system
medicine.medical_specialty endocrine system diseases biology Endocrinology Diabetes and Metabolism medicine.medical_treatment Thyroid Biological activity medicine.disease Pathology and Forensic Medicine Autoimmune thyroiditis chemistry.chemical_compound Endocrinology Immune system medicine.anatomical_structure chemistry Internal medicine medicine biology.protein Thyroglobulin Thyroid function Antibody Thiazole |
| Zdroj: | Problems of Endocrine Pathology. 57:43-49 |
| ISSN: | 2518-1432 2227-4782 |
| DOI: | 10.21856/j-pep.2016.3.05 |
| Popis: | The study of new biologically active compound PL-308 with immunomodulating properties on the thyroid function in rats with experimental autoimmune thyroiditis. It was determined that the introduction of PL-308 reduces autoimmune aggression by lowering the level of antibodies to thyroglobulin, increases the number of all subpopulations of T-lymphocytes, in particular Tsuppressors. It was observed normalization of the functional state of the thyroid gland. |
| Databáze: | OpenAIRE |
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