Chiral cyclic β-amino esters. Part II: Synthesis by diastereoselective reduction of enamino esters

Autor:	Jean-Claude Gramain, Christian Bellec, J. P. Celerier, D. Gardette, A. Bardou, Gérard Lhommet, Marie-Claude Fargeau-Bellassoued, Jerome Blot
Rok vydání:	1997
Předmět:	Reduction (complexity) chemistry.chemical_compound Hydrogen chemistry Amino esters Organic Chemistry Drug Discovery Diastereomer chemistry.chemical_element Organic chemistry Biochemistry Pyrrolidine Catalysis
Zdroj:	Tetrahedron Letters. 38:8511-8514
ISSN:	0040-4039
DOI:	10.1016/s0040-4039(97)10301-x
Popis:	Catalytic and chemical reductions of chiral pyrrolidine β-enamino esters provides corresponding β-amino esters with good to moderate diastereomer excesses. The unexpected major diastereomer 5 comes from a reduction process which amounts to an anti hydrogen addition.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::15bc7882d6c5002f05def0f25bd3cd06 https://doi.org/10.1016/s0040-4039(97)10301-x Zobrazit plný text záznamu Full Text from ScienceDirect