Cellular and molecular basis of skeletal muscle hystogenesis

Autor: O. V. Payushina, O. N. Sheveleva, V. I. Starostin
Rok vydání: 2012
Předmět:
Zdroj: Biology Bulletin. 39:495-503
ISSN: 1608-3059
1062-3590
Popis: The molecular basis of development and regeneration of skeletal muscles are reviewed. A model of parent-progeny relationships of mature animals’ skeletal muscles is proposed. Different cellular populations that contribute to myogenesis in vivo and in vitro are described. Both well-known typical cellular sources for muscle regeneration (satellite cells, muscle derived stem cells) and alternative cellular sources (CD133+ cells, pericytes, SP-cells from muscles and from bone marrow, mesangioblasts, embryonic stem cells and mesenchymal stromal cells) are presented. Moreover, some evidence for the existence of ectopic myogenic precursors in nonmuscle tissues is given.
Databáze: OpenAIRE