Efficacy, safety, and tolerability of pravastatin for the long-term treatment of patients with diverse types of hyperlipidemia: A multicenter prospective study
| Autor: | Soitsu Fukuchi, Kenji Mizuno, Susumu Niimura, Ken Katoh |
|---|---|
| Rok vydání: | 1993 |
| Předmět: |
Pharmacology
medicine.medical_specialty Chemotherapy business.industry Cholesterol medicine.medical_treatment nutritional and metabolic diseases medicine.disease Hydroxymethylglutaryl-CoA reductase Surgery chemistry.chemical_compound Tolerability chemistry Oral administration Internal medicine Hyperlipidemia medicine Pharmacology (medical) Prospective cohort study business Pravastatin medicine.drug |
| Zdroj: | Current Therapeutic Research. 54:500-507 |
| ISSN: | 0011-393X |
| DOI: | 10.1016/s0011-393x(05)80669-1 |
| Popis: | This multicenter study evaluated the efficacy, safety, and tolerability of pravastatin in the long-term treatment of patients with diverse types of primary hyperlipidemia. Of 103 patients from 21 centers, 59, 39, and 5 patients were judged to have type IIa, IIb, and IV hyperlipidemia, respectively. Patients followed an isocaloric diet throughout the trial. After a 4-week placebo period, treatment with pravastatin was initiated at 10 mg/day; the daily dose was increased to 20 mg after 4 weeks if the goal total cholesterol value ( |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|