Abstract 17005: Early Goal Directed Fluid Therapy for Patients With Heart Failure and Septic Shock

Autor:	Baher Al Abassi, Riya Job, Robert Chait, Jesus Pino, Fergie Ramos Tuarez, Kai Chen, Mohamed Abdul Qader, Pedro Torres
Rok vydání:	2020
Předmět:	medicine.medical_specialty Ejection fraction Ventricular function Septic shock business.industry Hemodynamics medicine.disease Fluid therapy Physiology (medical) Internal medicine Heart failure medicine Cardiology In patient Cardiology and Cardiovascular Medicine business
Zdroj:	Circulation. 142
ISSN:	1524-4539 0009-7322
DOI:	10.1161/circ.142.suppl_3.17005
Popis:	Introduction: The use of aggressive fluid therapy in patients with heart failure and reduced ejection fraction (HFrEF) who develop septic shock is controversial. Methods: This is a retrospective cohort study of 334 patients with heart failure (HF) and septic shock admitted to a tertiary cardiovascular center between 01/2015 and 06/2018. For this study, ejection fraction (EF) was dichotomized into Results: A total of 133(40%) patients had HFrEF, and 201(60%) patients had HFpEF (see Table 1, baseline characteristics). Early goal direct fluid therapy and vasopressors were equally implemented in all patients with HF that developed septic shock. Outcomes: There was no difference in in-hospital mortality for patients with HFrEF that developed septic shock when compared to patients with HFpEF, 64(48%) vs 102(51%) p=0.6542. Patients with HFrEF had a higher incidence of cardiogenic shock 25(19%) vs 9(4.5%) p Conclusions: Once patients with HF develop septic shock, the mortality is similar for both HFrEF and HFpEF. However, complications such as cardiogenic shock and 30-day readmission are more common in patients with HFrEF. A more individualized treatment approach is needed for this population.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::137ba9e39c89df8e5e5122aefde4c146 https://doi.org/10.1161/circ.142.suppl_3.17005 Zobrazit plný text záznamu