Minerva: July 2002
| Autor: | Snehal Lapsia, Paul Maguire, Jin J Bong, Mark Lansdown |
|---|---|
| Rok vydání: | 2002 |
| Předmět: |
medicine.medical_specialty
biology business.industry medicine.medical_treatment Cancer Immunosuppression General Medicine medicine.disease Betel biology.organism_classification Tobacco smoke chemistry.chemical_compound Amputation chemistry Internal medicine Prednisolone Medicine Lost to follow-up business Cotinine medicine.drug |
| Zdroj: | BMJ. 325:0207258 |
| ISSN: | 1756-1833 |
| DOI: | 10.1136/sbmj.0207258 |
| Popis: | Betel nut users put themselves at a high risk of oral cancer because the nuts induce chromosomal abnormalities. One analysis has identified that a loss in the short arm of chromosome 4 and a gain in the short arm of chromosome 9 are good predictors of prognosis. These losses are positively associated with poor outcome ( Oral Oncology 2002;38:266-73). Hospitality workers breathe in environmental tobacco smoke whether they like it or not. Saliva samples taken before and after a typical work shift found significantly higher cotinine concentrations in those working in places where smoking is permitted than in smoke-free premises. They also reported a higher prevalence of respiratory and irritation symptoms. The cotinine concentrations reported in this study have been linked with substantial involuntary risks for cancer and heart disease ( Tobacco Control 2002;11:125-9). A 37 year old man had a renal transplant performed 22 years ago and was taking azathioprine and prednisolone for immunosuppression. He was lost to follow up until he presented with a large squamous cell carcinoma on the dorsum of his right index finger. He subsequently underwent a ray amputation of his finger. … |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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