Effect of synthetic peptide fragments of β2-glycoprotein-I on the binding of antiphospholipid antibodies to cardiolipin-glycoprotein-I on the binding of antiphospholipid antibodies to cardiolipin
Autor: | Kuznetsova Tv, Evgeny Nasonov, Sidorova Mv, Tishchenko Va, Pal'keeva Me, Zh. D. Bespalova, A. G. Kobylyanskii |
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Rok vydání: | 1999 |
Předmět: |
chemistry.chemical_classification
biology Peptide General Medicine Primary and secondary antibodies General Biochemistry Genetics and Molecular Biology chemistry.chemical_compound chemistry Biochemistry Cardiolipin biology.protein lipids (amino acids peptides and proteins) Anticardiolipin antibodies Antibody Glycoprotein i β2 glycoprotein i |
Zdroj: | Bulletin of Experimental Biology and Medicine. 127:44-46 |
ISSN: | 1573-8221 0007-4888 |
DOI: | 10.1007/bf02432797 |
Popis: | The synthetic fragment of β2-glycoprotein-I peptide P5 (Phe280-Ser289) maximally inhibits the binding of anticardiolipin antibodies to cardiolipin. This β2-glycoprotein-I sequence probably reacts with negatively charged phospholipids and antibodies. |
Databáze: | OpenAIRE |
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