HYPERPHOSPHATEMIA IN END STAGE RENAL DISEASE: PREVALENCE AND PATIENTS CHARACTERISTICS OF MULTIETHNIC POPULATION OF UNITED ARAB EMIRATES
| Autor: | Padma G.M. Rao, Basset El Essawy, B S Sathvik, Syed Arman Rabbani, Martin Thomas Kurian |
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| Rok vydání: | 2017 |
| Předmět: |
musculoskeletal diseases
0301 basic medicine medicine.medical_specialty medicine.medical_treatment Pharmaceutical Science Disease urologic and male genital diseases Logistic regression End stage renal disease 03 medical and health sciences Hyperphosphatemia 0302 clinical medicine Internal medicine Hypertensive Nephropathy medicine Pharmacology business.industry nutritional and metabolic diseases medicine.disease female genital diseases and pregnancy complications 030104 developmental biology 030220 oncology & carcinogenesis Population study Hemodialysis business Body mass index |
| Zdroj: | International Journal of Pharmacy and Pharmaceutical Sciences. 9:283 |
| ISSN: | 0975-1491 |
| DOI: | 10.22159/ijpps.2017v9i12.22425 |
| Popis: | Objective: Hyperphosphatemia is significantly associated with increased mortality among end stage renal disease (ESRD) patients on hemodialysis. There is paucity of data on hyperphosphatemia in ESRD patients of the multiethnic population of United Arab Emirates (UAE). The study aimed to investigate the prevalence and characteristics of hyperphosphatemia in ESRD patients of the multiethnic population of UAE undergoing maintenance hemodialysis.Methods: Adults ESRD patients undergoing maintenance hemodialysis for more than six months at the study site were included. Demographic, clinical and biological data of the patients were collected. Patient characteristics were compared as per the serum phosphate level, between patients with or without hyperphosphatemia. Univariate and multivariate logistic regression analyses were carried out to identify the predictors of hyperphosphatemia.Results: Hyperphosphatemia was present in 73.8% of the study population, while 31.3% presented with high calcium-phosphate product. Univariate logistic analysis revealed that hyperphosphatemia was inversely correlated with age, hemoglobin, serum calcium, and hypertensive nephropathy as cause of renal disease, and positively correlated with female gender, expatriate status, body mass index (BMI), higher number of comorbidities, calcium-phosphate product and parathyroid hormone (PTH). Multivariate logistic regression model revealed that only age, BMI, hemoglobin and PTH independently correlated with hyperphosphatemia.Conclusion: We report a high prevalence of hyperphosphatemia in multiethnic study population undergoing maintenance hemodialysis at a secondary care hospital in UAE. In this study population, only age, BMI, hemoglobin and PTH were identified as independent predictors of hyperphosphatemia. |
| Databáze: | OpenAIRE |
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