Repurposing some older drugs that cross the blood-brain barrier and have potential anticancer activity to provide new treatment options for glioblastoma
| Autor: | Dayle Rundle-Thiele, Leah J. Cosgrove, Jennifer H. Martin, Richard Head |
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| Rok vydání: | 2015 |
| Předmět: |
Pharmacology
Oncology medicine.medical_specialty business.industry Treatment regimen Treatment options Patient survival medicine.disease Blood–brain barrier nervous system diseases 03 medical and health sciences 0302 clinical medicine medicine.anatomical_structure 030220 oncology & carcinogenesis Internal medicine medicine Pharmacology (medical) In patient business neoplasms Brain neoplasm 030217 neurology & neurosurgery Repurposing Glioblastoma |
| Zdroj: | British Journal of Clinical Pharmacology. 81:199-209 |
| ISSN: | 0306-5251 |
| Popis: | Glioblastoma is a brain neoplasm with limited 5-year survival rates. Developments of new treatment regimens that improve patient survival in patients with glioblastoma are needed. It is likely that a number of existing drugs used in other conditions have potential anticancer effects that offer significant survival benefit to glioblastoma patients. Identification of such drugs could provide a novel treatment paradigm. |
| Databáze: | OpenAIRE |
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