Fluorobenzo-1,4-thiazine oxides from bis-(vinylsulfinyl)-and bis(vinylsulfonyl)-fluorobenzenes and 2-aminoethanol

Autor:	Yu. T. Struchkov, Svetlana V. Amosova, L. N. II'icheva, V. N. Nesterov, G. M. Gavrilova, V. I. Gostevskaya
Rok vydání:	1996
Předmět:	chemistry.chemical_classification Nucleophilic addition Double bond Organic Chemistry Oxide chemistry.chemical_element Ring (chemistry) Medicinal chemistry Fluorobenzenes chemistry.chemical_compound chemistry Thiazine Fluorine Benzene
Zdroj:	Chemistry of Heterocyclic Compounds. 32:1023-1026
ISSN:	1573-8353 0009-3122
Popis:	It has been established that 1, 2, 4, 5-tetrafluoro-3, 6-bis (vinylsulfinyl)- and 1, 2, 4, 5-tetrafluoro-3, 6bis(vinylsulfonyl)benzenes react with 2-aminoethanol by nucleophilic addition at the activated double bond with replacement of fluorine atoms on the benzene ring by the amino group of 2-aminoethanol to give 4, 9-bis(2 hydroxyethyl)-5,10-difluoro-1, 2, 3, 4, 6, 7, 8, 9-octahydrobenzo[1, 2-b; 5, 4-b]di-1, 4-thiazine 1,6-dioxide and 1, 1, 6, 6-tetraoxide respectively.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::11d7539ec3427a0f38e6f83a38d3045a https://doi.org/10.1007/bf01164706 Zobrazit plný text záznamu Full text from SpringerLink