Open-angle glaucoma in an urban population in southern india
| Autor: | Catherine A. McCarty, Partha Mandal, Lalit Dandona, Rajesh K John, Rakhi Dandona, Srinivas Marmamula, Gullapalli N Rao |
|---|---|
| Rok vydání: | 2000 |
| Předmět: |
Intraocular pressure
education.field_of_study medicine.medical_specialty genetic structures medicine.diagnostic_test Open angle glaucoma business.industry Population Ocular hypertension Glaucoma medicine.disease eye diseases Ophthalmology medicine.anatomical_structure Eye examination medicine Gonioscopy sense organs business education Optic disc |
| Zdroj: | Ophthalmology. 107:1702-1709 |
| ISSN: | 0161-6420 |
| DOI: | 10.1016/s0161-6420(00)00275-x |
| Popis: | Objective To assess the prevalence and features of open-angle glaucoma in an urban population in southern India. Design A population-based cross-sectional study. Participants A total of 2522 persons (85.4% of those eligible) of all ages, including 1399 persons 30 years of age or older, from 24 clusters representative of the population of Hyderabad city. Testing The participants underwent an interview and detailed eye examination that included logarithm of minimum angle of resolution visual acuity, refraction, slit-lamp biomicroscopy, applanation tonometry, gonioscopy, dilatation, cataract grading, and stereoscopic fundus evaluation. Automated Humphrey threshold 24-2 visual fields (Humphrey Instruments Inc., San Leandro, CA) and optic disc photography were performed when indicated by standardized criteria for disc damage or if intraocular pressure (IOP) was 22 mmHg or more. Main outcome measures Definite primary open-angle glaucoma (POAG) was defined as obvious glaucomatous optic disc damage and visual field loss in the presence of an open-angle, and suspected POAG was defined as suspected glaucomatous optic disc damage without definite visual field loss. Ocular hypertension (OHT) was defined as IOP of 22 mmHg or more without glaucomatous optic disc damage or visual field loss in the presence of an open-angle. Glaucomatous optic disc damage or IOP of 22 mmHg or more secondary to an obvious cause and with an open-angle was defined as secondary open-angle glaucoma. Results Definite POAG, suspected POAG, and OHT were present in 27, 14, and 7 participants, respectively, with age- and gender-adjusted prevalence (95% confidence interval) of 1.62% (0.77%–2.48%), 0.79% (0.39%–1.41%), and 0.32% (0.10%–0.78%) in those 30 years of age or older, and 2.56% (1.22%–3.91%), 1.11% (0.43%–1.78%), and 0.42% (0.11%–1.12%) in those 40 years of age or older, respectively. The prevalence of POAG increased significantly with age using multivariate analysis ( P Conclusions The prevalence of open-angle glaucoma in this urban population in southern India is at least as much as that reported recently from white populations in developed countries. However, the vast majority of persons with glaucoma were undiagnosed in this population, and a large proportion of those having definite POAG already had severe glaucomatous damage. |
| Databáze: | OpenAIRE |
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