Indium Trichloride (InCl3) Catalyzed Synthesis of Fused 7-Azaindole Derivatives Using Domino Knoevenagel-Michael Reaction

Autor:	Yoginath B. Mule, Babasaheb P. Bandgar, Hemant V. Chavan, Pravin S. Bhale, Sakharam B. Dongare, Datta N. Surwase
Rok vydání:	2016
Předmět:	Reaction conditions 010405 organic chemistry Chemistry General Chemistry 010402 general chemistry 01 natural sciences High yielding Domino 0104 chemical sciences Catalysis Indium Trichloride Cascade reaction Michael reaction Organic chemistry Knoevenagel condensation
Zdroj:	Journal of the Chinese Chemical Society. 63:323-330
ISSN:	0009-4536
DOI:	10.1002/jccs.201500540
Popis:	An efficient and high yielding methodology developed for the synthesis of fused 7-azaindole derivatives via one pot multicomponent assembly process of cyclic 1,3-dicarbonyls with substituted aldehydes and 5-amino-1-tert-butyl-1H-pyrrole-3-carbonitrile. The transformation occurs via domino Knoevenagel- Michael reaction followed by intramolecular cyclization in the presence of catalytic amount of InCl3 (10 mol %). Mild reaction conditions, easy isolation of products, and good to excellent yields in a shorter period of time are the silent features of present methodology. Structures of all the newly prepared compounds have been corroborated by various spectroscopic methods.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::11aa5a322e32e046b1f4f8d5e46f8f9d https://doi.org/10.1002/jccs.201500540 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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