Adenos ine diphosphate-induced platelet aggregation in patients with coronary artery disease and concomitant anxiety and depression

Autor: M. I. Kadinskaya, E. V. Shlyakhto, N. G. Neznanov, I. Y. Efimova, A. V. Golubev, S N Kozlova, U. S. Krylova
Rok vydání: 2009
Předmět:
Zdroj: "Arterial’naya Gipertenziya" ("Arterial Hypertension"). 15:181-184
ISSN: 2411-8524
1607-419X
Popis: We studied the changes in adenosine diphosphate (ADP)-induced platelet aggregation in patients with coronary artery disease (CAD) and concomitant anxiety and depression. We found a significant reduction of platelet aggregation response (time of aggregation at ADP concentration 1,25 and 2,5 µM, maximum percentages of aggregation at ADP concentrarion 1,25 µM) in plasma of patients with CAD and concomitant anxiety and depression as compared with patients with CAD without anxiety and depression. Our results do not support hypothesis of an increased thrombosis in patients with CAD and anxiety and depression.
Databáze: OpenAIRE