Pancreas tissue concentration and pharmacokinetics analysis of vancomycin for severe acute pancreatitis: a case report
| Autor: | Chuhui Wang, Chao Li, Na He, Xiao-Xiao Li, Qing-Gang Ge, Suodi Zhai |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
genetic structures business.industry medicine.drug_class Antibiotics biochemical phenomena metabolism and nutrition medicine.disease Gastroenterology medicine.anatomical_structure Pharmacokinetics Internal medicine medicine Acute pancreatitis Vancomycin Pancreas business medicine.drug |
| DOI: | 10.22541/au.159103401.17486111 |
| Popis: | Antibiotic concentration in pancreas tissue is very important for the treatment of severe acute pancreatitis (SAP) with infection. We report a case of a 44-year-old female with SAP on treatment of vancomycin. The time courses of vancomycin concentration in serum and pancreas tissue of the patient was described. This case demonstrated that it took about 30 minutes for vancomycin to get through from serum to pancreas tissue and about 76% of vancomycin could move into pancreas tissue for SAP patients. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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