An expedient copper-catalysed asymmetric synthesis of γ-lactones and γ-lactams. Application to the synthesis of lucidulactone A
| Autor: | O. Stephen Ojo, David L. Hughes, Christopher J. Richards |
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| Rok vydání: | 2023 |
| Předmět: | |
| Zdroj: | Organic & Biomolecular Chemistry. 21:4144-4149 |
| ISSN: | 1477-0539 1477-0520 |
| DOI: | 10.1039/d3ob00563a |
| Popis: | The synthesis of β-aryl α,β-unsaturated lactones and lactams in high enantiomeric excess is described, and the key copper-catalysed reduction methodology with the parent Josiphos ligand is applied to the asymmetric synthesis of lucidulactone A. |
| Databáze: | OpenAIRE |
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