A case of acquired Thrombotic Thrombocytopenic Purpura (TTP) caused by acute severe hepatitis E: successfully treated by plasma exchange and rituximab

Autor: Yingwei ou, Yifan Xu, Zhaowang Tan, Lingxiao Pang, Shengqin Li, Qian li, Wenwei Cai, Yong Nan, Jianfeng Tu
Rok vydání: 2023
DOI: 10.21203/rs.3.rs-2691157/v1
Popis: With low morbidity and high mortality, Thrombotic Thrombocytopenic Purpura (TTP) has brought critical physical and economic burden to society and individual. Thrombocytopenia is very common in severe liver failure, and a variety of hepatitis viruses can induce immune thrombocytopenic purpura. However, it is extremely rare in HEV infection. We hereby report the case of a 53-year-old man who present with TTP caused by severe hepatitis E, and the patients recovered well after treatment. Thus, we propose considering that for patients with severe hepatitis or infection with notable platelet decline, AMAMTS13 testing is very necessary and beneficial for the accurate diagnosis and treatment.
Databáze: OpenAIRE