Body mass index, hyperglycemia, and stage of presentation at time of cancer diagnosis in Hispanic women
| Autor: | Anna Maria Di Marco, Omayra J. Gonzalez Pagan, Joe J Rodriguez, Juan C Orengo |
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| Rok vydání: | 2017 |
| Předmět: | |
| Zdroj: | Journal of Clinical Oncology. 35:e13052-e13052 |
| ISSN: | 1527-7755 0732-183X |
| DOI: | 10.1200/jco.2017.35.15_suppl.e13052 |
| Popis: | e13052 Background: Obesity prevalence among Hispanic communities is alarmingly high. The correlation between obesity and elevated blood glucose levels with increased cancer risk has remained controversial for several years. Thus, the main objectives of this study are: 1) to estimate the prevalence of obesity and overweight in a women cancer population; 2) to compare our findings with the general population; 3) to assess the stage at time of diagnosis by cancer site. Methods: An exploratory, cross-sectional study was conducted at one oncology women clinic located in Ponce, Puerto Rico. The medial records were selected by a Simple Random Sampling, all adult women with any type of cancer were included. Descriptive statistics were used to summarize patient demographics, morbidity, and clinical characteristics. Results: 216 medical records were reviewed. The distribution by age group was: 21-30 (n = 3 (1.4%); 31-35 (n = 35 (16.2%); 46-64 (n = 96(44.4%); ≥65 (n = 82(38%). The 50.5% (109) of the patients presented breast cancer, 24 (11.2%) uterine cancer and 17 (7.9%) colon cancer. FBS ≥ 126 was presented by 38 participants (19.6%). A BMI ≥ 30 was presented by 121 (56%) of the patients and 54 (25%) were overweight (81% of obesity and overweight). Obesity and overweight in women from Puerto Rico Behavioral Risk Surveillance System (PRBRFSS, 2014) presents a prevalence of 64% and Loren et al (2014) found a prevalence of 65.1% in women without cancer, comparing with our finding (81%) this difference is statistically significant (p < 0.05). A 26.9% (n = 58) of Hispanic women in our study presented diabetes vs 17.2% in the Hispanic women population (PRBRFSS, 2015) this difference is statistically significant (p < 0.05), controlling by cancer diagnosis. Analyzing stage (from I to IV) by breast cancer or not, we found a significant statistically difference (p < 0.001), 83.9% of breast cancer are stage I and II vs. 45.3% of no breast cancer. Conclusions: Our results suggest that a BMI ≥ 25 kg/m2 and diabetes are part of the profile of the Hispanic women with a diagnosis of a malignancy. Breast cancer is diagnosed at an earlier stage than any other malignancy, which could be explained by the amount of information available for breast cancer screening. |
| Databáze: | OpenAIRE |
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