Behavioural comorbidity in Tanzanian children with epilepsy: a community-based case-control study
| Autor: | Jim Todd, Jane Rogathe, Kathryn Burton, Richard Walker, Mark Swai, Charles R. Newton, Brian G. R. Neville, Ewan Hunter, Matthew J. Burton |
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| Rok vydání: | 2011 |
| Předmět: |
Pediatrics
medicine.medical_specialty Cross-sectional study business.industry Incidence (epidemiology) Case-control study Odds ratio medicine.disease Comorbidity Confidence interval Epilepsy Pharmacotherapy Developmental Neuroscience Pediatrics Perinatology and Child Health medicine Neurology (clinical) business |
| Zdroj: | Developmental Medicine & Child Neurology. 53:1135-1142 |
| ISSN: | 0012-1622 |
| DOI: | 10.1111/j.1469-8749.2011.04109.x |
| Popis: | Aim The aim of this study was to define the prevalence of and risk factors for behavioural disorders in children with epilepsy from a rural district of Tanzania by conducting a community-based case–control study. Method One hundred and twelve children aged 6 to 14 years (55 males, 57 females; median age 12y) with active epilepsy (at least two unprovoked seizures in the last 5y) were identified in a cross-sectional survey and included in this study. Children who were younger than 6 years were excluded in order to eliminate febrile seizures. Behaviour was assessed using the Rutter scale; children who scored 13 or more were considered to have disordered behaviour. A comparison group was made up of age- and sex-matched children without epilepsy (n=113; 57 males, 56 females; median age 12y). Results Behavioural disorders were diagnosed in 68 of 103 (66%) children with epilepsy and in 19 of 99 (19%) controls. Disordered behaviour was significantly more common in children with epilepsy than in the comparison group (univariate odds ratio 8.2; 95% confidence interval [CI] 4.3–15.6; p |
| Databáze: | OpenAIRE |
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