| Autor: |
Alan G. Walton, Carl R. McMillin |
| Rok vydání: |
1974 |
| Předmět: |
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| Zdroj: |
Journal of Colloid and Interface Science. 48:345-349 |
| ISSN: |
0021-9797 |
| Popis: |
A cell that allows the structure of adsorbed protein layers to be examined by transmission circular dichroism is described. Sensitivity of the technique is demonstrated by presentation of spectra obtained from the adsorption of two blood proteins [bovine fibrinogen and human clotting factor XII (Hageman factor)] on a quartz substrate. The former does not undergo a conformational change on adsorption: the latter becomes activated and suffers a major structural change. It is suggested that such methodology is useful in the investigation of the interaction of blood components with prospective polymeric prosthetic implants. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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