Diagnosis and choice of haemostatic therapy during surgery in patients with combined coagulation factor V and VIII defi ciency
| Autor: | A. I. Kostin, E. B. Orel, E. V. Yakovleva, P. S. Lavrova, A. M. Gasanov, I. V. Efimov, O. S. Pshenichnikova, N. I. Zozulya, V. L. Surin, N. V. Sats, M. Kh. Azimova, N. I. Konyashina |
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| Rok vydání: | 2021 |
| Předmět: |
Pediatrics
medicine.medical_specialty genetic structures biology business.industry Factor V Hematology 030204 cardiovascular system & hematology Coagulation factor V Blood Coagulation Factor V medicine.disease Haemophilia Comorbidity 03 medical and health sciences 0302 clinical medicine Von Willebrand disease Etiology biology.protein Medicine In patient business 030215 immunology |
| Zdroj: | Russian journal of hematology and transfusiology. 66:79-87 |
| ISSN: | 2411-3042 0234-5730 |
| DOI: | 10.35754/0234-5730-2021-66-1-79-87 |
| Popis: | Introduction. Among the most common congenital coagulopathies are haemophilia and Von Willebrand disease. These illnesses are often mimicked by orphan hereditary coagulopathies, including combined coagulation factor V and VIII deficiency.Aim — description of a clinical presentation, hampered diagnosis and choice of haemostatic therapy in a surgical patient with combined blood coagulation factor V and VIII deficiency.Main findings. We describe a clinical case of congenital combined factor V and VIII deficiency and detail the aetiology, frequency, localisation and intensity of haemorrhages. Comorbidity and surgical indications are demonstrated to require an inter-specialty medical involvement. |
| Databáze: | OpenAIRE |
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