Pediatric Inflammatory Multisystem Syndrome Associated With SARS-CoV-2
| Autor: | Juan Camilo Jaramillo-Bustamante, Raúl Bustos B, Franco Díaz, Pablo Cruces, Pablo Vásquez-Hoyos |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Pediatric intensive care unit
Pediatrics medicine.medical_specialty Myocarditis business.industry MEDLINE 030208 emergency & critical care medicine General Medicine Evidence-based medicine Disease medicine.disease_cause medicine.disease Mucocutaneous Lymph Node Syndrome 03 medical and health sciences 0302 clinical medicine hemic and lymphatic diseases 030225 pediatrics Pediatrics Perinatology and Child Health Emergency Medicine medicine Kawasaki disease business Coronavirus |
| Zdroj: | Pediatric Emergency Care. 37:44-47 |
| ISSN: | 1535-1815 0749-5161 |
| DOI: | 10.1097/pec.0000000000002306 |
| Popis: | Pediatric inflammatory multisystem syndrome temporally associated with severe acute respiratory syndrome coronavirus 2 (PIMS-TS) is infrequent, but children might present as a life-threatening disease. In a systematic quantitative review, we analyzed 11 studies of PIMS-TS, including 468 children reported before July 1, 2020. We found a myriad of clinical features, but we were able to describe common characteristics: previously healthy school-aged children, persistent fever and gastrointestinal symptoms, lymphopenia, and high inflammatory markers. Clinical syndromes such as myocarditis and Kawasaki disease were present in only one third of cases each one. Pediatric intensive care unit admission was frequent, although length of stay was less than 1 week, and mortality was low. Most patients received immunoglobulin or steroids, although the level of evidence for that treatment is low. The PIMS-ST was recently described, and the detailed quantitative pooled data will increase clinicians' awareness, improve diagnosis, and promptly start treatment. This analysis also highlights the necessity of future collaborative studies, given the heterogeneous nature of the PIMS-TS. |
| Databáze: | OpenAIRE |
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